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Indirect readout: detection of optimized subsequences and calculation of relative binding affinities using different DNA elastic potentials

Essential biological processes require that proteins bind to a set of specific DNA sites with tuned relative affinities. We focus on the indirect readout mechanism and discuss its theoretical description in relation to the present understanding of DNA elasticity on the rigid base pair level. Combini...

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Detalles Bibliográficos
Autores principales: Becker, Nils B., Wolff, Lars, Everaers, Ralf
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636474/
https://www.ncbi.nlm.nih.gov/pubmed/17038333
http://dx.doi.org/10.1093/nar/gkl683