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Indirect readout: detection of optimized subsequences and calculation of relative binding affinities using different DNA elastic potentials
Essential biological processes require that proteins bind to a set of specific DNA sites with tuned relative affinities. We focus on the indirect readout mechanism and discuss its theoretical description in relation to the present understanding of DNA elasticity on the rigid base pair level. Combini...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636474/ https://www.ncbi.nlm.nih.gov/pubmed/17038333 http://dx.doi.org/10.1093/nar/gkl683 |