Cargando…
Indirect readout: detection of optimized subsequences and calculation of relative binding affinities using different DNA elastic potentials
Essential biological processes require that proteins bind to a set of specific DNA sites with tuned relative affinities. We focus on the indirect readout mechanism and discuss its theoretical description in relation to the present understanding of DNA elasticity on the rigid base pair level. Combini...
Autores principales: | Becker, Nils B., Wolff, Lars, Everaers, Ralf |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636474/ https://www.ncbi.nlm.nih.gov/pubmed/17038333 http://dx.doi.org/10.1093/nar/gkl683 |
Ejemplares similares
-
Indirect readout in drug-DNA recognition: role of sequence-dependent DNA conformation
por: Araúzo-Bravo, Marcos J., et al.
Publicado: (2008) -
ReadOut: structure-based calculation of direct and indirect readout energies and specificities for protein–DNA recognition
por: Ahmad, Shandar, et al.
Publicado: (2006) -
Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA
por: Veprintsev, Dmitry B., et al.
Publicado: (2008) -
Protein disorder-to-order transition enhances the nucleosome-binding affinity of H1
por: Sridhar, Akshay, et al.
Publicado: (2020) -
DNAffinity: a machine-learning approach to predict DNA binding affinities of transcription factors
por: Barissi, Sandro, et al.
Publicado: (2022)