Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus

In the first step of retroviral integration, integrase cleaves the linear viral DNA within its long terminal repeat (LTR) immediately 3′ to the CA dinucleotide step, resulting in a reactive 3′ OH on one strand and a 5′ two base overhang on the complementary strand. In order to investigate the struct...

Descripción completa

Detalles Bibliográficos
Autores principales: Montaño, Sherwin P., Coté, Marie L., Roth, Monica J., Georgiadis, Millie M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636480/
https://www.ncbi.nlm.nih.gov/pubmed/17003051
http://dx.doi.org/10.1093/nar/gkl693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636480/
https://www.ncbi.nlm.nih.gov/pubmed/17003051
http://dx.doi.org/10.1093/nar/gkl693

Ejemplares similares