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Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus
In the first step of retroviral integration, integrase cleaves the linear viral DNA within its long terminal repeat (LTR) immediately 3′ to the CA dinucleotide step, resulting in a reactive 3′ OH on one strand and a 5′ two base overhang on the complementary strand. In order to investigate the struct...
Autores principales: | Montaño, Sherwin P., Coté, Marie L., Roth, Monica J., Georgiadis, Millie M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636480/ https://www.ncbi.nlm.nih.gov/pubmed/17003051 http://dx.doi.org/10.1093/nar/gkl693 |
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