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Using DNA pools for genotyping trios

The genotyping of mother–father–child trios is a very useful tool in disease association studies, as trios eliminate population stratification effects and increase the accuracy of haplotype inference. Unfortunately, the use of trios for association studies may reduce power, since it requires the gen...

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Detalles Bibliográficos
Autores principales: Beckman, Kenneth B., Abel, Kenneth J., Braun, Andreas, Halperin, Eran
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636483/
https://www.ncbi.nlm.nih.gov/pubmed/17020923
http://dx.doi.org/10.1093/nar/gkl700