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Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1

The orphan nuclear receptor nurr1 (NR4A2) is an essential transcription factor for the acquisition and maintenance of the phenotype of dopamine (DA)-synthesizing neurons in the mesencephalon. Although structurally related to ligand-regulated nuclear receptors, nurr1 is functionally atypical due to i...

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Detalles Bibliográficos
Autores principales: Sacchetti, Paola, Carpentier, Rodolphe, Ségard, Pascaline, Olivé-Cren, Cécile, Lefebvre, Philippe
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636490/
https://www.ncbi.nlm.nih.gov/pubmed/17020917
http://dx.doi.org/10.1093/nar/gkl712