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Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1
The orphan nuclear receptor nurr1 (NR4A2) is an essential transcription factor for the acquisition and maintenance of the phenotype of dopamine (DA)-synthesizing neurons in the mesencephalon. Although structurally related to ligand-regulated nuclear receptors, nurr1 is functionally atypical due to i...
Autores principales: | Sacchetti, Paola, Carpentier, Rodolphe, Ségard, Pascaline, Olivé-Cren, Cécile, Lefebvre, Philippe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636490/ https://www.ncbi.nlm.nih.gov/pubmed/17020917 http://dx.doi.org/10.1093/nar/gkl712 |
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