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A high throughput method for genome-wide analysis of retroviral integration

Retroviral and lentiviral vectors integrate their DNA into the host cell genome leading to stable transgene expression. Integration preferentially occurs in the proximity of active genes, and may in some case disturb their activity, with adverse toxic consequences. To efficiently analyze high number...

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Detalles Bibliográficos
Autores principales: Mantovani, Julie, Holic, Nathalie, Martinez, Kelly, Danos, Olivier, Perea, Javier
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636494/
https://www.ncbi.nlm.nih.gov/pubmed/17028098
http://dx.doi.org/10.1093/nar/gkl716