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Lactate levels in severe malarial anaemia are associated with haemozoin-containing neutrophils and low levels of IL-12

BACKGROUND: Hyperlactataemia is often associated with a poor outcome in severe malaria in African children. To unravel the complex pathophysiology of this condition the relationship between plasma lactate levels, parasite density, pro- and anti-inflammatory cytokines, and haemozoin-containing leucoc...

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Detalles Bibliográficos
Autores principales: Casals-Pascual, Climent, Kai, Oscar, Lowe, Brett, English, Mike, Williams, Thomas N, Maitland, Kathryn, Newton, Charles RCJ, Peshu, Norbert, Roberts, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636645/
https://www.ncbi.nlm.nih.gov/pubmed/17087827
http://dx.doi.org/10.1186/1475-2875-5-101