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Stromal Derived Factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis

Renal cell carcinoma (RCC) is characterized by organ-specific metastases. The chemokine stromal derived factor-1 (SDF-1/CXCL12) and its receptor CXCR4 have been suggested to regulate organ-specific metastasis in various other cancers. On this basis, we hypothesized that the biological axis of CXCL12...

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Detalles Bibliográficos
Autores principales: Pan, Judong, Mestas, Javier, Burdick, Marie D, Phillips, Roderick J, Thomas, George V, Reckamp, Karen, Belperio, John A, Strieter, Robert M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636662/
https://www.ncbi.nlm.nih.gov/pubmed/17083723
http://dx.doi.org/10.1186/1476-4598-5-56