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Funneled Landscape Leads to Robustness of Cell Networks: Yeast Cell Cycle

We uncovered the underlying energy landscape for a cellular network. We discovered that the energy landscape of the yeast cell-cycle network is funneled towards the global minimum (G0/G1 phase) from the experimentally measured or inferred inherent chemical reaction rates. The funneled landscape is q...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Huang, Bo, Xia, Xuefeng, Sun, Zhirong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636676/
https://www.ncbi.nlm.nih.gov/pubmed/17112311
http://dx.doi.org/10.1371/journal.pcbi.0020147