Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control

BACKGROUND: We have previously constructed a doxycycline (dox)-dependent HIV-1 variant by incorporating the Tet-On gene regulatory system into the viral genome. Replication of this HIV-rtTA virus is driven by the dox-inducible transactivator protein rtTA, and can be switched on and off at will. We p...

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Detalles Bibliográficos
Autores principales: Zhou, Xue, Vink, Monique, Berkhout, Ben, Das, Atze T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637113/
https://www.ncbi.nlm.nih.gov/pubmed/17094796
http://dx.doi.org/10.1186/1742-4690-3-82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637113/
https://www.ncbi.nlm.nih.gov/pubmed/17094796
http://dx.doi.org/10.1186/1742-4690-3-82

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