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Iron Regulation of the Major Virulence Factors in the AIDS-Associated Pathogen Cryptococcus neoformans

Iron overload is known to exacerbate many infectious diseases, and conversely, iron withholding is an important defense strategy for mammalian hosts. Iron is a critical cue for Cryptococcus neoformans because the fungus senses iron to regulate elaboration of the polysaccharide capsule that is the ma...

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Detalles Bibliográficos
Autores principales: Jung, Won Hee, Sham, Anita, White, Rick, Kronstad, James W
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637126/
https://www.ncbi.nlm.nih.gov/pubmed/17121456
http://dx.doi.org/10.1371/journal.pbio.0040410