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Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment.
A physiologically based pharmacokinetic (PBPK) model was developed that provides a comprehensive description of the kinetics of trichloroethylene (TCE) and its metabolites, trichloroethanol (TCOH), trichloroacetic acid (TCA), and dichloroacetic acid (DCA), in the mouse, rat, and human for both oral...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637761/ https://www.ncbi.nlm.nih.gov/pubmed/10807559 |