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Inhaled crocidolite mutagenicity in lung DNA.

We used transgenic mice carrying the lacI reporter gene to study the mutagenesis potential of asbestos crocidolite. The animals were exposed by nose-only inhalation to an aerosol containing 5.75 mg/m(3) crocidolite dust for 6 hr/day and 5 consecutive days. After 1, 4, and 12 weeks, we examined four...

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Detalles Bibliográficos
Autores principales: Rihn, B, Coulais, C, Kauffer, E, Bottin, M C, Martin, P, Yvon, F, Vigneron, J C, Binet, S, Monhoven, N, Steiblen, G, Keith, G
Formato: Texto
Lenguaje:English
Publicado: 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1638032/
https://www.ncbi.nlm.nih.gov/pubmed/10753093