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Pattern statistics on Markov chains and sensitivity to parameter estimation
BACKGROUND: In order to compute pattern statistics in computational biology a Markov model is commonly used to take into account the sequence composition. Usually its parameter must be estimated. The aim of this paper is to determine how sensitive these statistics are to parameter estimation, and wh...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1647278/ https://www.ncbi.nlm.nih.gov/pubmed/17044916 http://dx.doi.org/10.1186/1748-7188-1-17 |