Long intervals of stasis punctuated by bursts of positive selection in the seasonal evolution of influenza A virus

BACKGROUND: The interpandemic evolution of the influenza A virus hemagglutinin (HA) protein is commonly considered a paragon of rapid evolutionary change under positive selection in which amino acid replacements are fixed by virtue of their effect on antigenicity, enabling the virus to evade immune...

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Detalles Bibliográficos
Autores principales: Wolf, Yuri I, Viboud, Cecile, Holmes, Edward C, Koonin, Eugene V, Lipman, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1647279/
https://www.ncbi.nlm.nih.gov/pubmed/17067369
http://dx.doi.org/10.1186/1745-6150-1-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1647279/
https://www.ncbi.nlm.nih.gov/pubmed/17067369
http://dx.doi.org/10.1186/1745-6150-1-34

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