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Long intervals of stasis punctuated by bursts of positive selection in the seasonal evolution of influenza A virus
BACKGROUND: The interpandemic evolution of the influenza A virus hemagglutinin (HA) protein is commonly considered a paragon of rapid evolutionary change under positive selection in which amino acid replacements are fixed by virtue of their effect on antigenicity, enabling the virus to evade immune...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1647279/ https://www.ncbi.nlm.nih.gov/pubmed/17067369 http://dx.doi.org/10.1186/1745-6150-1-34 |