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Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence

Diversity in the pathophysiology of breast cancer frustrates therapeutic progress. We need to understand how mechanisms activated by specific combinations of oncogenes, tumor suppressors, and hormonal signaling pathways govern response to therapy and prognosis. A recent series of investigations cond...

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Detalles Bibliográficos
Autores principales: Tilli, Maddalena T, Furth, Priscilla A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165023/
https://www.ncbi.nlm.nih.gov/pubmed/12817992
http://dx.doi.org/10.1186/bcr614