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SLE - Systemic lupus erythematosus: a BLySful, yet BAFFling, disorder

BLyS/BAFF (B-lymphocyte stimulator/B-cell activating factor) is a vital B-cell survival factor. Overexpression of BLyS in mice may lead to systemic-lupus-erythematosus-like (SLE-like) disease, and BLyS overexpression is common in human SLE. Treatment of SLE-prone mice with a BLyS antagonist ameliora...

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Detalles Bibliográficos
Autor principal: Stohl, William
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165050/
https://www.ncbi.nlm.nih.gov/pubmed/12723979
http://dx.doi.org/10.1186/ar755