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Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis

The pathogenesis of rheumatoid arthritis (RA) and osteoarthritis (OA) remains obscure, although angiogenesis appears to play an important role. We recently confirmed an overexpression of two angiogenic factors, namely vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell gr...

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Detalles Bibliográficos
Autores principales: Giatromanolaki, Alexandra, Sivridis, Efthimios, Maltezos, Efstratios, Athanassou, Nick, Papazoglou, Dimitrios, Gatter, Kevin C, Harris, Adrian L, Koukourakis, Michael I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165055/
https://www.ncbi.nlm.nih.gov/pubmed/12823854
http://dx.doi.org/10.1186/ar756