The stereospecificity of flobufen metabolism in isolated guinea pig hepatocytes

BACKGROUND: Flobufen (F) is an original nonsteroidal anti-inflammatory drug with one center of chirality. 4-Dihydroflobufen (DHF), compound with two chiral centers, is the main metabolite of F in microsomes and cytosol in all standard laboratory animals. This work describes the biotransformation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Kral, Radim, Skalova, Lenka, Szotakova, Barbora, Velik, Jakub, Schroterova, Ladislava, Babu, Yogeeta N, Wsol, Vladimir
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165433/
https://www.ncbi.nlm.nih.gov/pubmed/12791169
http://dx.doi.org/10.1186/1471-2210-3-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165433/
https://www.ncbi.nlm.nih.gov/pubmed/12791169
http://dx.doi.org/10.1186/1471-2210-3-5

Ejemplares similares