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The stereospecificity of flobufen metabolism in isolated guinea pig hepatocytes

BACKGROUND: Flobufen (F) is an original nonsteroidal anti-inflammatory drug with one center of chirality. 4-Dihydroflobufen (DHF), compound with two chiral centers, is the main metabolite of F in microsomes and cytosol in all standard laboratory animals. This work describes the biotransformation of...

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Detalles Bibliográficos
Autores principales:	Kral, Radim, Skalova, Lenka, Szotakova, Barbora, Velik, Jakub, Schroterova, Ladislava, Babu, Yogeeta N, Wsol, Vladimir
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165433/ https://www.ncbi.nlm.nih.gov/pubmed/12791169 http://dx.doi.org/10.1186/1471-2210-3-5

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