Effects of nimesulide on kainate-induced in vitro oxidative damage in rat brain homogenates

BACKGROUND: The cyclooxygenase-2 inhibitor nimesulide is able to reduce kainate-induced oxidative stress in vivo. Here we investigate if this effect is mediated by the direct antioxidant properties of nimesulide using a well-characterized in vitro model of kainate toxicity. RESULTS: Exposure of rat...

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Detalles Bibliográficos
Autores principales: Candelario-Jalil, Eduardo, Sonia León, Olga
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165434/
https://www.ncbi.nlm.nih.gov/pubmed/12807536
http://dx.doi.org/10.1186/1471-2210-3-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165434/
https://www.ncbi.nlm.nih.gov/pubmed/12807536
http://dx.doi.org/10.1186/1471-2210-3-7

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