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Effects of nimesulide on kainate-induced in vitro oxidative damage in rat brain homogenates
BACKGROUND: The cyclooxygenase-2 inhibitor nimesulide is able to reduce kainate-induced oxidative stress in vivo. Here we investigate if this effect is mediated by the direct antioxidant properties of nimesulide using a well-characterized in vitro model of kainate toxicity. RESULTS: Exposure of rat...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165434/ https://www.ncbi.nlm.nih.gov/pubmed/12807536 http://dx.doi.org/10.1186/1471-2210-3-7 |