Adrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesity

BACKGROUND: Elevated glucocorticoid production and reduced hypothalamic POMC mRNA can cause obese phenotypes. Conversely, adrenalectomy can reverse obese phenotypes caused by the absence of leptin, a model in which glucocorticoid production is elevated. Adrenalectomy also increases hypothalamic POMC...

Descripción completa

Detalles Bibliográficos
Autores principales: Makimura, Hideo, Mizuno, Tooru M, Beasley, Joe, Silverstein, Jeffrey H, Mobbs, Charles V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165436/
https://www.ncbi.nlm.nih.gov/pubmed/12795810
http://dx.doi.org/10.1186/1472-6793-3-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165436/
https://www.ncbi.nlm.nih.gov/pubmed/12795810
http://dx.doi.org/10.1186/1472-6793-3-4

Ejemplares similares