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Adrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesity
BACKGROUND: Elevated glucocorticoid production and reduced hypothalamic POMC mRNA can cause obese phenotypes. Conversely, adrenalectomy can reverse obese phenotypes caused by the absence of leptin, a model in which glucocorticoid production is elevated. Adrenalectomy also increases hypothalamic POMC...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165436/ https://www.ncbi.nlm.nih.gov/pubmed/12795810 http://dx.doi.org/10.1186/1472-6793-3-4 |