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Impact of Nonsense-Mediated mRNA Decay on the Global Expression Profile of Budding Yeast

Nonsense-mediated mRNA decay (NMD) is a eukaryotic mechanism of RNA surveillance that selectively eliminates aberrant transcripts coding for potentially deleterious proteins. NMD also functions in the normal repertoire of gene expression. In Saccharomyces cerevisiae, hundreds of endogenous RNA Polym...

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Detalles Bibliográficos
Autores principales: Guan, Qiaoning, Zheng, Wei, Tang, Shijie, Liu, Xiaosong, Zinkel, Robert A, Tsui, Kam-Wah, Yandell, Brian S, Culbertson, Michael R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1657058/
https://www.ncbi.nlm.nih.gov/pubmed/17166056
http://dx.doi.org/10.1371/journal.pgen.0020203