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Structure-based discovery of inhibitors of the YycG histidine kinase: New chemical leads to combat Staphylococcus epidermidis infections

BACKGROUND: Coagulase-negative Staphylococcus epidermidis has become a major frequent cause of infections in relation to the use of implanted medical devices. The pathogenicity of S. epidermidis has been attributed to its capacity to form biofilms on surfaces of medical devices, which greatly increa...

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Detalles Bibliográficos
Autores principales: Qin, Zhiqiang, Zhang, Jian, Xu, Bin, Chen, Lili, Wu, Yang, Yang, Xiaomei, Shen, Xu, Molin, Soeren, Danchin, Antoine, Jiang, Hualiang, Qu, Di
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1660542/
https://www.ncbi.nlm.nih.gov/pubmed/17094812
http://dx.doi.org/10.1186/1471-2180-6-96