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The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice

BACKGROUND: Streptococcus pneumoniae possesses large zinc metalloproteinases on its surface. To analyse the importance in virulence of three of these metalloproteinases, intranasal challenge of MF1 outbred mice was carried out using a range of infecting doses of wild type and knock-out pneumococcal...

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Detalles Bibliográficos
Autores principales: Chiavolini, Damiana, Memmi, Guido, Maggi, Tiziana, Iannelli, Francesco, Pozzi, Gianni, Oggioni, Marco R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC166150/
https://www.ncbi.nlm.nih.gov/pubmed/12841855
http://dx.doi.org/10.1186/1471-2180-3-14