Paclitaxel chemotherapy: from empiricism to a mechanism-based formulation strategy

Paclitaxel is an anticancer agent effective for the treatment of breast, ovarian, lung, and head and neck cancer. Because of water insolubility, paclitaxel is formulated with the micelle-forming vehicle Cremophor EL to enhance drug solubility. However, the addition of Cremophor EL results in hyperse...

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Detalles Bibliográficos
Autores principales: Scripture, Charity D, Figg, William D, Sparreboom, Alex
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2005
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1661618/
https://www.ncbi.nlm.nih.gov/pubmed/18360550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1661618/
https://www.ncbi.nlm.nih.gov/pubmed/18360550

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