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Inhibitors of selectin functions in the treatment of inflammatory skin disorders

Selectins mediate tethering and rolling of leukocytes to the vascular endothelium, the first adhesive step in the recruitment of immune cells to inflamed tissues. Thus, selectins play a key role in the pathogenesis of common inflammatory skin disorders such as atopic dermatitis or psoriasis. As a co...

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Detalles Bibliográficos
Autor principal: Schön, Michael P
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1661630/
https://www.ncbi.nlm.nih.gov/pubmed/18360560