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Stem cells, senescence, neosis and self-renewal in cancer

We describe the basic tenets of the current concepts of cancer biology, and review the recent advances on the suppressor role of senescence in tumor growth and the breakdown of this barrier during the origin of tumor growth. Senescence phenotype can be induced by (1) telomere attrition-induced senes...

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Detalles Bibliográficos
Autores principales: Rajaraman, Rengaswami, Guernsey, Duane L, Rajaraman, Murali M, Rajaraman, Selva R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664585/
https://www.ncbi.nlm.nih.gov/pubmed/17092342
http://dx.doi.org/10.1186/1475-2867-6-25