Population Pharmacokinetics of Artesunate and Dihydroartemisinin following Intra-Rectal Dosing of Artesunate in Malaria Patients

BACKGROUND: Intra-rectal artesunate has been developed as a potentially life-saving treatment of severe malaria in rural village settings where administration of parenteral antimalarial drugs is not possible. We studied the population pharmacokinetics of intra-rectal artesunate and the relationship...

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Detalles Bibliográficos
Autores principales: Simpson, Julie A, Agbenyega, Tsiri, Barnes, Karen I, Perri, Gianni Di, Folb, Peter, Gomes, Melba, Krishna, Sanjeev, Krudsood, Srivicha, Looareesuwan, Sornchai, Mansor, Sharif, McIlleron, Helen, Miller, Raymond, Molyneux, Malcolm, Mwenechanya, James, Navaratnam, Visweswaran, Nosten, Francois, Olliaro, Piero, Pang, Lorrin, Ribeiro, Isabela, Tembo, Madalitso, van Vugt, Michele, Ward, Steve, Weerasuriya, Kris, Win, Kyaw, White, Nicholas J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664603/
https://www.ncbi.nlm.nih.gov/pubmed/17132053
http://dx.doi.org/10.1371/journal.pmed.0030444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664603/
https://www.ncbi.nlm.nih.gov/pubmed/17132053
http://dx.doi.org/10.1371/journal.pmed.0030444

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