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Expression of Xenobiotic Metabolizing Enzymes in Different Lung Compartments of Smokers and Nonsmokers

BACKGROUND: Cytochrome P450 monooxygenases (CYP) play an important role in the defense against inhaled toxicants, and expression of CYP enzymes may differ among various lung cells and tissue compartments. METHODS: We studied the effects of tobacco smoke in volunteers and investigated gene expression...

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Detalles Bibliográficos
Autores principales: Thum, Thomas, Erpenbeck, Veit J., Moeller, Julia, Hohlfeld, Jens M., Krug, Norbert, Borlak, Jürgen
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665420/
https://www.ncbi.nlm.nih.gov/pubmed/17107849
http://dx.doi.org/10.1289/ehp.8861