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Drosophila NMNAT Maintains Neural Integrity Independent of Its NAD Synthesis Activity
Wallerian degeneration refers to a loss of the distal part of an axon after nerve injury. Wallerian degeneration slow (Wld(s)) mice overexpress a chimeric protein containing the NAD synthase NMNAT (nicotinamide mononucleotide adenylyltransferase 1) and exhibit a delay in axonal degeneration. Current...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665629/ https://www.ncbi.nlm.nih.gov/pubmed/17132048 http://dx.doi.org/10.1371/journal.pbio.0040416 |