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Endogenous MMTV Proviruses Induce Susceptibility to Both Viral and Bacterial Pathogens

Most inbred mice carry germline proviruses of the retrovirus, mouse mammary tumor virus (MMTV) (called Mtvs), which have multiple replication defects. A BALB/c congenic mouse strain lacking all endogenous Mtvs (Mtv-null) was resistant to MMTV oral and intraperitoneal infection and tumorigenesis comp...

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Detalles Bibliográficos
Autores principales: Bhadra, Sanchita, Lozano, Mary M, Payne, Shelley M, Dudley, Jaquelin P
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665650/
https://www.ncbi.nlm.nih.gov/pubmed/17140288
http://dx.doi.org/10.1371/journal.ppat.0020128