NHEJ-deficient DT40 cells have increased levels of immunoglobulin gene conversion: evidence for a double strand break intermediate

Activation-induced cytidine deaminase (AID) likely initiates immunoglobulin gene-conversion (GC) by deaminating cytidines within the V-region of chicken B-cells. However, the intervening DNA lesion required to initiate GC remains elusive. GC could be initiated by a single strand break or a double st...

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Detalles Bibliográficos
Autores principales: Tang, Ephraim S., Martin, Alberto
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1669771/
https://www.ncbi.nlm.nih.gov/pubmed/17142237
http://dx.doi.org/10.1093/nar/gkl830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1669771/
https://www.ncbi.nlm.nih.gov/pubmed/17142237
http://dx.doi.org/10.1093/nar/gkl830

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