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Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury

Leukotrienes are increased locally in idiopathic pulmonary fibrosis. Furthermore, a role for these arachidonic acid metabolites has been thoroughly characterized in the animal bleomycin model of lung fibrosis by using different gene knock-out settings. We investigated the efficacy of pharmacological...

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Detalles Bibliográficos
Autores principales: Failla, Marco, Genovese, Tiziana, Mazzon, Emanuela, Gili, Elisa, Muià, Carmelo, Sortino, Mariangela, Crimi, Nunzio, Caputi, Achille P, Cuzzocrea, Salvatore, Vancheri, Carlo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1676006/
https://www.ncbi.nlm.nih.gov/pubmed/17118201
http://dx.doi.org/10.1186/1465-9921-7-137