Computational Model Explains High Activity and Rapid Cycling of Rho GTPases within Protein Complexes

Formation of multiprotein complexes on cellular membranes is critically dependent on the cyclic activation of small GTPases. FRAP-based analyses demonstrate that within protein complexes, some small GTPases cycle nearly three orders of magnitude faster than they would spontaneously cycle in vitro. A...

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Detalles Bibliográficos
Autores principales: Goryachev, Andrew B, Pokhilko, Alexandra V
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1676031/
https://www.ncbi.nlm.nih.gov/pubmed/17140284
http://dx.doi.org/10.1371/journal.pcbi.0020172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1676031/
https://www.ncbi.nlm.nih.gov/pubmed/17140284
http://dx.doi.org/10.1371/journal.pcbi.0020172

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