Molecular surveillance of mutations in the cytochrome b gene of Plasmodium falciparum in Gabon and Ethiopia

BACKGROUND: Atovaquone is part of the antimalarial drug combination atovaquone-proguanil (Malarone(®)) and inhibits the cytochrome bc(1 )complex of the electron transport chain in Plasmodium spp. Molecular modelling showed that amino acid mutations are clustered around a putative atovaquone-binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Gebru, Tamirat, Hailu, Asrat, Kremsner, Peter G, Kun, Jürgen FJ, Grobusch, Martin P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679811/
https://www.ncbi.nlm.nih.gov/pubmed/17118179
http://dx.doi.org/10.1186/1475-2875-5-112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679811/
https://www.ncbi.nlm.nih.gov/pubmed/17118179
http://dx.doi.org/10.1186/1475-2875-5-112

Ejemplares similares