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Molecular surveillance of mutations in the cytochrome b gene of Plasmodium falciparum in Gabon and Ethiopia

BACKGROUND: Atovaquone is part of the antimalarial drug combination atovaquone-proguanil (Malarone(®)) and inhibits the cytochrome bc(1 )complex of the electron transport chain in Plasmodium spp. Molecular modelling showed that amino acid mutations are clustered around a putative atovaquone-binding...

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Detalles Bibliográficos
Autores principales:	Gebru, Tamirat, Hailu, Asrat, Kremsner, Peter G, Kun, Jürgen FJ, Grobusch, Martin P
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679811/ https://www.ncbi.nlm.nih.gov/pubmed/17118179 http://dx.doi.org/10.1186/1475-2875-5-112

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