Gene function prediction from congruent synthetic lethal interactions in yeast

We predicted gene function using synthetic lethal genetic interactions between null alleles in Saccharomyces cerevisiae. Phenotypic and protein interaction data indicate that synthetic lethal gene pairs function in parallel or compensating pathways. Congruent gene pairs, defined as sharing synthetic...

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Detalles Bibliográficos
Autores principales: Ye, Ping, Peyser, Brian D, Pan, Xuewen, Boeke, Jef D, Spencer, Forrest A, Bader, Joel S
Formato: Texto
Lenguaje:English
Publicado: 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681444/
https://www.ncbi.nlm.nih.gov/pubmed/16729061
http://dx.doi.org/10.1038/msb4100034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681444/
https://www.ncbi.nlm.nih.gov/pubmed/16729061
http://dx.doi.org/10.1038/msb4100034

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