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Threshold responses to morphogen gradients by zero-order ultrasensitivity

Translating a graded morphogen distribution into tight response borders is central to all developmental processes. Yet, the molecular mechanisms generating such behavior are poorly understood. During patterning of the Drosophila embryonic ventral ectoderm, a graded mitogen-activated protein kinase (...

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Detalles Bibliográficos
Autores principales: Melen, Gustavo J, Levy, Sagi, Barkai, Naama, Shilo, Ben-Zion
Formato: Texto
Lenguaje:English
Publicado: 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681448/
https://www.ncbi.nlm.nih.gov/pubmed/16729063
http://dx.doi.org/10.1038/msb4100036