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The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation

Deciphering regulatory events that drive malignant transformation represents a major challenge for systems biology. Here, we analyzed genome-wide transcription profiling of an in vitro cancerous transformation process. We focused on a cluster of genes whose expression levels increased as a function...

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Detalles Bibliográficos
Autores principales: Tabach, Yuval, Milyavsky, Michael, Shats, Igor, Brosh, Ran, Zuk, Or, Yitzhaky, Assif, Mantovani, Roberto, Domany, Eytan, Rotter, Varda, Pilpel, Yitzhak
Formato: Texto
Lenguaje:English
Publicado: 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681464/
https://www.ncbi.nlm.nih.gov/pubmed/16729057
http://dx.doi.org/10.1038/msb4100030