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Systems-level analyses identify extensive coupling among gene expression machines

Here, we develop computational methods to assess and consolidate large, diverse protein interaction data sets, with the objective of identifying proteins involved in the coupling of multicomponent complexes within the yeast gene expression pathway. From among ∼43 000 total interactions and 2100 prot...

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Detalles Bibliográficos
Autores principales: Maciag, Karolina, Altschuler, Steven J, Slack, Michael D, Krogan, Nevan J, Emili, Andrew, Greenblatt, Jack F, Maniatis, Tom, Wu, Lani F
Formato: Texto
Lenguaje:English
Publicado: 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681477/
https://www.ncbi.nlm.nih.gov/pubmed/16738550
http://dx.doi.org/10.1038/msb4100045