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Residues crucial for maintaining short paths in network communication mediate signaling in proteins
Here, we represent protein structures as residue interacting networks, which are assumed to involve a permanent flow of information between amino acids. By removal of nodes from the protein network, we identify fold centrally conserved residues, which are crucial for sustaining the shortest pathways...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681495/ https://www.ncbi.nlm.nih.gov/pubmed/16738564 http://dx.doi.org/10.1038/msb4100063 |