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Dynamic analysis of optimality in myocardial energy metabolism under normal and ischemic conditions
To better understand the dynamic regulation of optimality in metabolic networks under perturbed conditions, we reconstruct the energetic-metabolic network in mammalian myocardia using dynamic flux balance analysis (DFBA). Additionally, we modified the optimal objective from the maximization of ATP p...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681503/ https://www.ncbi.nlm.nih.gov/pubmed/16760902 http://dx.doi.org/10.1038/msb4100071 |