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Cheminformatics methods for novel nanopore analysis of HIV DNA termini

BACKGROUND: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This information is derived from observation of changes in ionic channel current blockade "signal" upon that molecule's...

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Detalles Bibliográficos
Autores principales: Winters-Hilt, Stephen, Landry, Matthew, Akeson, Mark, Tanase, Maria, Amin, Iftekhar, Coombs, Amy, Morales, Eric, Millet, John, Baribault, Carl, Sendamangalam, Srikanth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1683570/
https://www.ncbi.nlm.nih.gov/pubmed/17118144
http://dx.doi.org/10.1186/1471-2105-7-S2-S22