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SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks

BACKGROUND: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology system and further assist for disease therapy. However, there are relatively few methods to evaluate the importance of prot...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Li, Dong, Zhang, Jiyang, Zhu, Yunping, He, Fuchu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1683949/
https://www.ncbi.nlm.nih.gov/pubmed/17129367
http://dx.doi.org/10.1186/1471-2105-7-515